As an arrogant young doctor, trailing degrees from a string of prestigious schools, Christina Yang is brutally frank, on the professional make and more than a little put off by patients and drudge work. "Aggressive little witch!" one old hospital hand dubs Yang, after the insensitive doc lassos a cancer patient just to participate in the interesting surgery to come. Sandra Oh's Asian version of a Buster Keaton deadpan delivers wonderful double-takes -- but when this tough cookie goes soft, as she sometimes does, her face radiates fierce truth and beauty.