Meredith and Derek get one last shot at success in their clinical trial; the surgeons work together to free a boy from a block of cement; Izzie helps Alex care for Rebecca; Lexie... Full summary

Dr. Wyatt refuses to let Meredith give up on therapy; Alex learns the truth about Rebecca's medical condition; the Chief insists Erica perform a risky surgery on his mentor.

The nurses' complaints about Mark Sloan's trysts result in a date-and-tell policy; Cristina is forced to face her feelings for Burke; Meredith and Derek admit a veteran into their... Full summary

Addison returns to Seattle Grace to perform an operation and is surprised by all the changes in the lives of her former co-workers; Derek and Meredith's clinical trial has its first... Full summary

Six weeks after Derek and Meredith ended their relationship, Meredith, Alex, Izzie and Cristina compete in a surgical contest, with Bailey serving as judge; George and Lexie adjust to... Full summary

Bailey's family faces a medical trauma just as her marriage falls apart; George's mother makes a surprise visit; a faith healer challenges Erica and Alex's belief in traditional... Full summary

Meredith furiously works to save the life of a paramedic trapped inside an ambulance; Lexie holds a patient's life in her hands; Derek must rely on a nurse's help to save a patient;... Full summary

An ambulance crash endangers the lives of the paramedics involved; Bailey treats a patient who refuses her help; Ava returns for Alex and meets his other girlfriend.

Teenagers fill the ER after a school-bus crash; Bailey treats a patient who was her high-school crush; Derek goes on a date with a fellow doctor; Thatcher enters the ER looking for... Full summary

George and Izzie test their romantic chemistry; Derek asks for more than a physical connection with Meredith; Mark develops a crush on a fellow surgeon; Callie finds her role as chief... Full summary